Learn about Ford E-350 / E-450 (2021-2025) fuse box and relay’s locations, functions, and maintenance tips for optimal vehicle electrical system.
The Ford E-350 and E-450 (2021-2025) remain trusted members of the E-Series lineup, known for their robust design and adaptability for commercial applications. These vehicles are available primarily as cutaway vans and chassis cabs, offering a solid foundation for custom builds like shuttle buses, ambulances, delivery trucks, and RV conversions. Their durable frame and powerful engine options make them ideal for heavy-duty work while ensuring reliability and functionality.
The electrical system of these vehicles is supported by a well-organized fuse box and relay system. The primary fuse box, located in the engine compartment near the battery, safeguards crucial components like the lights, horn, and ignition system. A secondary fuse panel is often situated inside the cabin for additional electrical accessories. Relays, which manage high-power functions such as the starter, fuel pump, and cooling fans, are housed near the fuse boxes. Regular inspection of fuses and relays ensures the uninterrupted operation of these vital systems.
MUST READ: DYI – How to Check Car Fuses?
(2021-2025) Ford E-350 / E-450 fuse box and relay with Diagram
WARNING
- Never replace a fuse with one that has a higher amperage rating.
- A fuse with a too-high amperage could damage the electrical part and cause a fire.
- On no account should fuses be repaired (e.g. patched up with tin foil or wire) as this may cause serious damage elsewhere in the electrical circuit or cause a fire.
- If a fuse blows repeatedly, do not keep replacing it. Instead, have the cause for the repeated short circuit or overload tracked and fixed.
- Terminal and harness assignments for individual connectors will vary depending on vehicle equipment level, model, and market.
Ford E-350 / E-450 (2021-2025) fuse assignment
Ford E-350 / E-450 Year of production: 2021, 2022, 2023, 2024, 2025
Passenger Compartment Fuse Box:
The fuse panel is to the left-hand side of the brake pedal and mounted onto the lower left-hand cowl panel. Remove the fuse panel cover to access the fuses. If your vehicle has dual batteries, disconnecting the primary under hood battery does not remove power from all circuits.
Engine Compartment Fuse Box:
The engine compartment fuse box is in the engine compartment. It has high-current fuses that protect your vehicle’s main electrical systems from overloads. If you disconnect and reconnect the battery, you need to reset some features. If your vehicle has dual batteries, disconnecting the primary under hood battery does not remove power from all circuits.
Fuse Box Diagrams
2021
Passenger Compartment Fuse Box
List of fuses in the passenger compartment fuse box (2021)
| № | A | Protected Component |
|---|---|---|
| 1 | – | Not used. |
| 2 | 10A | Left-hand front and right-hand front door lock switch (cutaway). Inverter (cutaway). Connector (stripped chassis). |
| 3 | 7.5A | Power mirror switch (cutaway). |
| – | Not used (stripped chassis). | |
| 4 | 20A | Trailer brake control. |
| 5 | 20A | Not used (spare). |
| 6 | 10A | Not used (spare). |
| 7 | 10A | Not used (spare). |
| 8 | 10A | Not used (spare). |
| 9 | 10A | Not used (spare). |
| 10 | – | Not used. |
| 11 | – | Not used. |
| 12 | 7.5A | Smart datalink connector. Enterprise wired-in-device. |
| 13 | 7.5A | Cluster. Steering column control module. |
| 14 | 15A | Not used (spare). |
| 15 | 15A | Not used (spare). |
| 16 | – | Not used. |
| 17 | 7.5A | Not used. |
| 18 | 7.5A | Climate mode switch. |
| 19 | 5A | Radio transceiver module. |
| 20 | 5A | Ignition switch. |
| 21 | 5A | Not used. |
| 22 | 5A | Body builder B-pillar connector (cutaway). |
| 5A | Not used (stripped chassis). | |
| 23 | 30A | Not used (spare). |
| 24 | 30A | Not used (spare). |
| 25 | 20A | Not used (spare). |
| 26 | 30A | Not used (spare). |
| 27 | 30A | Not used (spare). |
| 28 | 30A | Not used (spare). |
| 29 | 15A | Upfitter interface module (cutaway). |
| – | Not used (stripped chassis). | |
| 30 | 5A | Not used (spare). |
| 31 | 10A | Smart datalink connector. |
| 32 | 20A | Radio. |
| 33 | – | Not used. |
| 34 | 30A | Not used (spare). |
| 35 | 5A | Tow haul switch. |
| 36 | 15A | Rear view mirror (cutaway). Rear view camera (cutaway). |
| – | Not used (stripped chassis). | |
| 37 | 20A | Not used (spare). |
| 38 | 30A | Rear window switches and motors (cutaway). |
| – | Not used (stripped chassis). | |
| Note: Spare fuse amperage may vary. | ||
Engine Compartment Fuse Box
List of fuses in the engine compartment fuse box (2021)
| № | A | Protected Component |
|---|---|---|
| 1 | 20A | Horn. |
| 2 | 50A | Blower motor. |
| 3 | – | Not used. |
| 4 | 30A | Starter relay. |
| 5 | 20A | Not used (spare). |
| 6 | 20A | Upfitter relay 4 (cutaway). Not used (spare) (stripped chassis). |
| 8 | – | Not used. |
| 10 | – | Not used. |
| 12 | 20A | Power point 4. |
| 13 | 10A | Yaw sensor (stripped chassis). Not used (spare) (cutaway). |
| 14 | 10A | Forward looking radar (cutaway). Not used (spare) (stripped chassis). |
| 15 | – | Not used. |
| 15 | – | Not used. |
| 17 | 10A | Powertrain control module run/start feed. |
| 18 | 10A | Anti-lock brake system run/start feed. |
| 19 | – | Not used. |
| 20 | 30A | Wiper power. |
| 21 | – | Not used. |
| 22 | 10A | Wiper module (stripped chassis). Not used (spare) (cutaway). |
| 23 | – | Not used. |
| 24 | 40A | Body control module – run power in feed 2. |
| 25 | 50A | Body control module – run power in feed 1. |
| 25 | – | Not used. |
| 27 | 20A | Body builder frame connector. |
| 28 | – | Not used. |
| 29 | 10A | B+power 12 V(special order vehicle). |
| 30 | 30A | Power driver seat (cutaway). Not used (spare) (stripped chassis). |
| 31 | – | Not used. |
| 32 | 20A | Vehicle power 1. |
| 33 | 20A | Vehicle power 2. |
| 34 | 10A | Vehicle power 3. |
| 35 | 20A | Vehicle power 4. |
| 35 | – | Not used. |
| 37 | – | Not used. |
| 38 | 10A | Washer relay (stripped chassis). Not used (spare) (cutaway). |
| 39 | – | Not used. |
| 41 | 30A | Trailer brake control connector. |
| 43 | 30A | Instrument panei connector (stripped chassis). Not used (spare) (cutaway). |
| 45 | – | Not used. |
| 45 | 10A | A/C clutch. |
| 47 | 40A | Upfitter relay 1 (cutaway). Not used (spare) (stripped chassis). |
| 48 | – | Not used. |
| 49 | 30A | Pump electronics module. |
| 50 | 15A | Injectors. |
| 51 | 20A | Power point 1. |
| 52 | 50A | B-pillar vehicle connector (cutaway). Not used (spare) (stripped chassis). |
| 53 | 30A | Trailer tow park lamps. |
| 54 | 40A | Upfitter 2 relay (cutaway). Not used (spare) (stripped chassis). |
| 55 | 20A | Upfitter 3 relay (cutaway). Not used (spare) (stripped chassis). |
| 56 | 20A | Power point 2 prep B-pillar connector. |
| 58 | 5A | USB smart charger. |
| 59 | 10A | Park lamps 1 (special order vehicle). |
| 60 | – | Not used. |
| 61 | – | Not used. |
| 62 | – | Not used. |
| 63 | – | Not used. |
| 64 | – | Not used. |
| 65 | – | Not used. |
| 66 | – | Not used. |
| 67 | – | Not used. |
| 69 | – | Not used. |
| 70 | 40A | Inverter. |
| 71 | 30A | Anti-lock brake system valves. |
| 72 | 10A | Brake on and off switch. |
| 73 | – | Not used. |
| 74 | – | Not used. |
| 75 | – | Not used. |
| 76 | 60A | Anti-lock brake system pump. |
| 77 | 30A | Voltage quality module power – body control module. |
| 78 | 10A | Trailer tow stop lamps. |
| 79 | – | Not used. |
| 80 | 10A | Trailer tow backup lamps. |
| 81 | – | Not used. |
| 82 | 5A | Run/start fuse – upfitter relays (cutaway). B+ fuse – upfitter relay. |
| 83 | – | Not used. |
| 84 | – | Not used. |
| 85 | – | Not used. |
| 85 | – | Not used. |
| 87 | – | Not used. |
| 88 | – | Not used. |
| 89 | – | Not used. |
| 91 | 40A | B-pillar (cutaway). Instrument panei (stripped chassis). |
| 93 | 10A | Park lamps 3 (special order vehicle). |
| 94 | 10A | Park lamps 2 (special order vehicle). |
| 95 | 20A | Stop lamp relay. |
| 95 | – | Not used. |
| 97 | 50A | Engine. B-pillar vehicle connector. Instrument panei. |
| 98 | 30A | Trailer tow battery charge. |
| 99 | 40A | Instrument panei connector. |
| 100 | – | Not used. |
| 101 | – | Not used. |
| 102 | – | Not used. |
| 103 | – | Not used. |
| 104 | – | Not used. |
| 105 | 15A | Trailer tow right-hand and left-hand stop and direction indicator relay power. |
| Relay | ||
| R02 | – | Powertrain control module. Power relay. |
| R05 | – | Not used. |
| Note: Spare fuse amperage may vary. | ||
2022
Passenger Compartment Fuse Box
List of fuses in the passenger compartment fuse box (2022)
| № | A | Protected Component |
|---|---|---|
| 1 | – | Not used. |
| 2 | 10A | Left-hand front and right-hand front door lock switch (cutaway). Inverter (cutaway). Connector (stripped chassis). |
| 3 | 7.5A | Power mirror switch (cutaway). |
| – | Not used (stripped chassis). | |
| 4 | 20A | Not used (spare). |
| 5 | 20A | Not used (spare). |
| 6 | 10A | Not used (spare). |
| 7 | 10A | Not used (spare). |
| 8 | 5A | Not used (spare). |
| 9 | 5A | Not used (spare). |
| 10 | – | Not used. |
| 11 | – | Not used. |
| 12 | 7.5A | Smart datalink connector. |
| 13 | 7.5A | Cluster. Steering column control module. |
| 14 | 15A | Not used (spare). |
| 15 | 15A | Not used (spare). |
| 16 | – | Not used. |
| 17 | 7.5A | Not used. |
| 18 | 7.5A | R/S feed for Front blend actuator/climate mode switch (cutaway). R/S feed to strip chassis connector (stripped chassis). |
| 19 | 5A | Radio transceiver module and telematics control unit. Telematics control unit. |
| 20 | 5A | Ignition switch. |
| 21 | 5A | Not used. |
| 22 | 5A | Body builder B-pillar connector (cutaway). |
| 5A | Not used (stripped chassis). | |
| 23 | 30A | Not used (spare). |
| 24 | 30A | Not used (spare). |
| 25 | 20A | Not used (spare). |
| 26 | 30A | Not used (spare). |
| 27 | 30A | Not used (spare). |
| 28 | 30A | Not used (spare). |
| 29 | 15A | Upfitter interface module (cutaway). |
| – | Not used (stripped chassis). | |
| 30 | 5A | Not used (spare). |
| 31 | 10A | Smart datalink connector. |
| 32 | 20A | Radio (cutaway). |
| 33 | – | Not used. |
| 34 | 30A | Not used (spare). |
| 35 | 5A | Tow haul switch. |
| 36 | 15A | Rear view mirror (cutaway). Camera lane departure (cutaway). |
| – | Not used (stripped chassis). | |
| 37 | 20A | Not used (spare). |
| 38 | 30A | Power window switches and motors (cutaway). |
| – | Not used (stripped chassis). | |
| Note: Spare fuse amperage may vary. | ||
Engine Compartment Fuse Box
List of fuses in the engine compartment fuse box (2022)
| № | A | Protected Component |
|---|---|---|
| 1 | 20A | Horn. |
| 2 | 50A | Blower motor. |
| 3 | – | Not used. |
| 4 | 30A | Starter relay. |
| 5 | – | Not used. |
| 6 | 20A | Upfitter relay 4 (cutaway). Not used (spare) (stripped chassis). |
| 8 | – | Not used. |
| 10 | – | Not used. |
| 12 | 20A | Power point 4. |
| 13 | 10A | Yaw sensor (stripped chassis). Not used (spare) (cutaway). |
| 14 | 10A | Forward looking radar (cutaway). Not used (spare) (stripped chassis). |
| 15 | – | Not used. |
| 16 | – | Not used. |
| 17 | 10A | Powertrain control module run/start feed. |
| 18 | 10A | Anti-lock brake system run/start feed. |
| 19 | – | Not used. |
| 20 | 30A | Wiper power. |
| 21 | – | Not used. |
| 22 | 10A | Wiper module (stripped chassis). Not used (spare) (cutaway). |
| 23 | – | Not used. |
| 24 | 40A | Body control module – run power in feed 2. |
| 25 | 50A | Body control module – run power in feed 1. |
| 26 | – | Not used. |
| 27 | 20A | Body builder frame connector. |
| 28 | – | Not used. |
| 29 | 10A | B+ power 12 V (special order vehicle). |
| 30 | 30A | Power driver seat (cutaway). Not used (spare) (stripped chassis). |
| 31 | – | Not used. |
| 32 | 20A | Vehicle power 1. |
| 33 | 20A | Vehicle power 2. |
| 34 | 10A | Vehicle power 3. |
| 35 | 20A | Vehicle power 4. |
| 36 | – | Not used. |
| 37 | – | Not used. |
| 38 | 10A | Washer relay (stripped chassis). Not used (spare) (cutaway). |
| 39 | – | Not used. |
| 41 | 30A | Trailer brake control connector. |
| 43 | 30A | Instrument panel connector (stripped chassis). Not used (spare) (cutaway). |
| 45 | – | Not used. |
| 46 | 10A | A/C clutch. |
| 47 | 40A | Upfitter relay 1 (cutaway). Not used (spare) (stripped chassis). |
| 48 | – | Not used. |
| 49 | 30A | Pump electronics module. |
| 50 | 15A | Injectors. |
| 51 | 20A | Power point 1. |
| 52 | 50A | Power at all times (PAAT) Aux AC Prep on B-pillar vehicle connector (cutaway). Not used (spare) (stripped chassis). |
| 53 | 30A | Trailer tow park lamps. |
| 54 | 40A | R/S feed on instrument panel connector. |
| 55 | 20A | Upfitter 3 relay (cutaway). Not used (spare) (stripped chassis). |
| 56 | 20A | Power point 2 prep B-pillar connector. |
| 58 | 5A | USB smart charger. |
| 59 | 10A | Park lamps 1 (special order vehicle). |
| 60 | – | Not used. |
| 61 | – | Not used. |
| 62 | – | Not used. |
| 63 | – | Not used. |
| 64 | – | Not used. |
| 65 | – | Not used. |
| 66 | – | Not used. |
| 67 | – | Not used. |
| 69 | – | Not used. |
| 70 | 40A | Inverter. |
| 71 | 30A | Anti-lock brake system valves. |
| 72 | 10A | Brake on and off switch. |
| 73 | – | Not used. |
| 74 | – | Not used. |
| 75 | – | Not used. |
| 76 | 60A | Anti-lock brake system pump. |
| 77 | 30A | Voltage quality module power – body control module. |
| 78 | 10A | Trailer tow stoplamps. |
| 79 | – | Not used. |
| 80 | 10A | Trailer tow backup lamps. |
| 81 | – | Not used. |
| 82 | 5A | Upfitter switch (factory location for ignition power). |
| 83 | 5A | Upfitter switch (optional location for power at all times). |
| 84 | – | Not used. |
| 85 | – | Not used. |
| 86 | – | Not used. |
| 87 | – | Not used. |
| 88 | – | Not used. |
| 89 | – | Not used. |
| 91 | 40A | Hot at all times (HAAT) / B+PWR on B-Pillar connector (cutaway). Battery Power on instru-ment panel connector(stripped chassis). |
| 93 | 10A | Park lamps 3 (special order vehicle). |
| 94 | 10A | Park lamps 2 (special order vehicle). |
| 95 | 20A | Stoplamp relay. |
| 96 | – | Not used. |
| 97 | 50A | Battery Power on Engine. B-pillar vehicle connector. Instrument panel. |
| 98 | 30A | Trailer tow battery charge. |
| 99 | 40A | Upfitter 2 relay (cutaway). Not used (spare) (stripped chassis). |
| 100 | – | Not used. |
| 101 | – | Not used. |
| 102 | – | Not used. |
| 103 | – | Not used. |
| 104 | – | Not used. |
| 105 | 15A | Trailer tow right-hand and left-hand stoplamp and direction indicator relay power. |
| Note: Spare fuse amperage may vary. | ||
2023
Passenger Compartment Fuse Box
List of fuses in the passenger compartment fuse box (2023)
| № | A | Protected Component |
|---|---|---|
| 1 | – | Not used. |
| 2 | 10A | Left-hand front and right-hand front door lock switch (cutaway). Inverter (cutaway). Connector (stripped chassis). |
| 3 | 7.5A | Power mirror switch (cutaway). |
| – | Not used (stripped chassis). | |
| 4 | 20A | Not used (spare). |
| 5 | 20A | Not used (spare). |
| 6 | 10A | Not used (spare). |
| 7 | 10A | Not used (spare). |
| 8 | 5A | Not used (spare). |
| 9 | 5A | Not used (spare). |
| 10 | – | Not used. |
| 11 | – | Not used. |
| 12 | 7.5A | Smart datalink connector. |
| 13 | 7.5A | Cluster. Steering column control module. |
| 14 | 15A | Not used (spare). |
| 15 | 15A | Not used (spare). |
| 15 | – | Not used. |
| 17 | 7.5A | Not used. |
| 18 | 7.5A | R/S feed for Front blend actuator/climate mode switch (cutaway). R/S feed to strip chassis connector (stripped chassis). |
| 19 | 5A | Radio transceiver module and telematics control unit. Telematics control unit. |
| 20 | 5A | Ignition switch. |
| 21 | 5A | Not used. |
| 22 | 5A | Body builder B-pillar connector (cutaway). |
| 5A | Not used (stripped chassis). | |
| 23 | 30A | Not used (spare). |
| 24 | 30A | Not used (spare). |
| 25 | 20A | Not used (spare). |
| 26 | 30A | Not used (spare). |
| 27 | 30A | Not used (spare). |
| 28 | 30A | Not used (spare). |
| 29 | 15A | Upfitter interface module (cutaway). |
| – | Not used (stripped chassis). | |
| 30 | 5A | Not used (spare). |
| 31 | 10A | Smart datalink connector. |
| 32 | 20A | Radio (cutaway). |
| 33 | – | Not used. |
| 34 | 30A | Not used (spare). |
| 35 | 5A | Tow haul switch. |
| 36 | 15A | Rear view mirror (cutaway). Camera lane departure (cutaway). |
| – | Not used (stripped chassis). | |
| 37 | 20A | Not used (spare). |
| 38 | 30A | Power window switches and motors (cutaway). |
| – | Not used (stripped chassis). | |
| Note: Spare fuse amperage may vary. | ||
Engine Compartment Fuse Box
List of fuses in the engine compartment fuse box (2023)
| № | A | Protected Component |
|---|---|---|
| 1 | 20A | Horn. |
| 2 | 50A | Blower motor. |
| 3 | – | Not used. |
| 4 | 30A | Starter relay. |
| 5 | – | Not used. |
| 6 | 20A | Upfitter relay 4 (cutaway). Not used (spare) (stripped chassis). |
| 8 | – | Not used. |
| 10 | – | Not used. |
| 12 | 20A | Power point 4. |
| 13 | 10A | Yaw sensor (stripped chassis). Not used (spare) (cutaway). |
| 14 | 10A | Forward looking radar (cutaway). Not used (spare) (stripped chassis). |
| 15 | – | Not used. |
| 15 | – | Not used. |
| 17 | 10A | Powertrain control module run/start feed. |
| 18 | 10A | Anti-lock brake system run/start feed. |
| 19 | – | Not used. |
| 20 | 30A | Wiper power. |
| 21 | – | Not used. |
| 22 | 10A | Wiper module (stripped chassis). Not used (spare) (cutaway). |
| 23 | – | Not used. |
| 24 | 40A | Body control module – run power in feed 2. |
| 25 | 50A | Body control module – run power in feed 1. |
| 26 | – | Not used. |
| 27 | 20A | Body builder frame connector. |
| 28 | – | Not used. |
| 29 | 10A | B+power 12 V(special order vehicle). |
| 30 | 30A | Power driver seat (cutaway). Not used (spare) (stripped chassis). |
| 31 | – | Not used. |
| 32 | 20A | Vehicle power 1. |
| 33 | 20A | Vehicle power 2. |
| 34 | 10A | Vehicle power 3. |
| 35 | 20A | Vehicle power 4. |
| 36 | – | Not used. |
| 37 | – | Not used. |
| 38 | 10A | Washer relay (stripped chassis). Not used (spare) (cutaway). |
| 39 | – | Not used. |
| 41 | 30A | Trailer brake control connector. |
| 43 | 30A | Instrument panel connector (stripped chassis). Not used (spare) (cutaway). |
| 45 | – | Not used. |
| 46 | 10A | A/C clutch. |
| 47 | 40A | Upfitter relay 1 (cutaway). Not used (spare) (stripped chassis). |
| 48 | – | Not used. |
| 49 | 30A | Pump electronics module. |
| 50 | 15A | Fuel injectors. |
| 51 | 20A | Power point 1. |
| 52 | 50A | Power at all times (PAAT) Aux AC prep on B-pillar vehicle connector (cutaway). Not used (spare) (stripped chassis). |
| 53 | 30A | Trailer tow park lamps. |
| 54 | 40A | R/S feed on instrument panel connector. |
| 55 | 20A | Upfitter 3 relay (cutaway). Not used (spare) (stripped chassis). |
| 56 | 20A | Power point 2 prep B-pillar connector. |
| 58 | 5A | USB smart charger. |
| 59 | 10A | Park lamps 1 (special order vehicle). |
| 60 | – | Not used. |
| 61 | – | Not used. |
| 62 | – | Not used. |
| 63 | – | Not used. |
| 64 | – | Not used. |
| 65 | – | Not used. |
| 66 | – | Not used. |
| 67 | – | Not used. |
| 69 | – | Not used. |
| 70 | 40A | Inverter. |
| 71 | 30A | Anti-lock brake system valves. |
| 72 | 10A | Brake on and off switch. |
| 73 | – | Not used. |
| 74 | – | Not used. |
| 75 | – | Not used. |
| 76 | 60A | Anti-lock brake system pump. |
| 77 | 30A | Voltage quality module power – body control module. |
| 78 | 10A | Trailer tow stoplamps. |
| 79 | – | Not used. |
| 80 | 10A | Trailer tow backup lamps. |
| 81 | – | Not used. |
| 82 | 5A | Upfitter switch (factory location for ignition power). |
| 83 | 5A | Upfitter switch (optional location for power at all times). |
| 84 | – | Not used. |
| 85 | – | Not used. |
| 86 | – | Not used. |
| 87 | – | Not used. |
| 88 | – | Not used. |
| 89 | – | Not used. |
| 91 | 40A | Hot at all times (HAAT) / B+PWR on B-pillar connector (cutaway). |
| Battery power on instrument panel connector(stripped chassis). | ||
| 93 | 10A | Park lamps 3 (special order vehicle). |
| 94 | 10A | Park lamps 2 (special order vehicle). |
| 95 | 20A | Stoplamp relay. |
| 96 | – | Not used. |
| 97 | 50A | Battery power to Engine, B-pillar and instrument panel vehicle connectors. |
| 98 | 30A | Trailer tow battery charge. |
| 99 | 40A | Upfitter 2 relay (cutaway). Not used (spare) (stripped chassis). |
| 100 | – | Not used. |
| 101 | – | Not used. |
| 102 | – | Not used. |
| 103 | – | Not used. |
| 104 | – | Not used. |
| 105 | 15A | Trailer tow right-hand and left-hand stoplamp and direction indicator relay power. |
| Note: Spare fuse amperage may vary. | ||
2024
Passenger Compartment Fuse Box
List of fuses in the passenger compartment fuse box (2024)
| № | A | Protected Component |
|---|---|---|
| 1 | – | Not used. |
| 2 | 10A | Left-hand front and right-hand front door lock switch (cutaway). Inverter (cutaway). Connector (stripped chassis). |
| 3 | 7.5A | Power mirror switch (cutaway). |
| – | Not used (stripped chassis). | |
| 4 | 20A | Not used (spare). |
| 5 | 20A | Not used (spare). |
| 6 | 10A | Not used (spare). |
| 7 | 10A | Not used (spare). |
| 8 | 5A | Not used (spare). |
| 9 | 5A | Not used (spare). |
| 10 | – | Not used. |
| 11 | – | Not used. |
| 12 | 7.5A | Smart datalink connector. |
| 13 | 7.5A | Cluster. Steering column control module. |
| 14 | 15A | Not used (spare). |
| 15 | 15A | Not used (spare). |
| 15 | – | Not used. |
| 17 | 7.5A | Not used. |
| 18 | 7.5A | Run/start feed for front blend actuator/climate mode switch (cutaway). Run/start feed to stripped chassis connector (stripped chassis). |
| 19 | 5A | Radio transceiver module and telematics control unit (cutaway). Telematics control unit (stripped chassis). |
| 20 | 5A | Ignition switch. |
| 21 | 5A | Not used. |
| 22 | 5A | Body builder B-pillar connector (cutaway). |
| 5A | Not used (stripped chassis). | |
| 23 | 30A | Not used (spare). |
| 24 | 30A | Not used (spare). |
| 25 | 20A | Not used (spare). |
| 25 | 30A | Not used (spare). |
| 27 | 30A | Not used (spare). |
| 28 | 30A | Not used (spare). |
| 29 | 15A | Upfitter interface module (cutaway). |
| – | Not used (stripped chassis). | |
| 30 | 5A | Not used (spare). |
| 31 | 10A | Smart datalink connector. |
| 32 | 20A | Radio (cutaway). |
| 33 | – | Not used. |
| 34 | 30A | Not used (spare). |
| 35 | 5A | Tow haul switch. |
| 36 | 15A | Rear view mirror (cutaway). Camera lane departure (cutaway). |
| – | Not used (stripped chassis). | |
| 37 | 20A | Not used (spare). |
| 38 | 30A | Power window switches and motors (cutaway). |
| – | Not used (stripped chassis). | |
| Note: Spare fuse amperage may vary. | ||
Engine Compartment Fuse Box
List of fuses in the engine compartment fuse box (2024)
| № | A | Protected Component |
|---|---|---|
| 1 | 20A | Horn. |
| 2 | 50A | Blower motor. |
| 3 | – | Not used. |
| 4 | 30A | Starter relay. |
| 5 | 20A | Power point 3. |
| 6 | 20A | Upfitter relay 4 (cutaway). Not used (spare) (stripped chassis). |
| 8 | – | Not used. |
| 10 | – | Not used. |
| 12 | 20A | Power point 4. |
| 13 | 10A | Yaw sensor (stripped chassis). Not used (spare) (cutaway). |
| 14 | 10A | Forward looking radar (cutaway). Not used (spare) (stripped chassis). |
| 15 | – | Not used. |
| 15 | – | Not used. |
| 17 | 10A | Powertrain control module run/start feed. |
| 18 | 10A | Anti-lock brake system run/start feed. |
| 19 | – | Not used. |
| 20 | 30A | Wiper power. |
| 21 | – | Not used. |
| 22 | 10A | Wiper module (stripped chassis). Not used (spare) (cutaway). |
| 23 | – | Not used. |
| 24 | 40A | Body control module – run power in feed 2. |
| 25 | 50A | Body control module – run power in feed 1. |
| 25 | – | Not used. |
| 27 | 20A | Body builder frame connector. |
| 28 | – | Not used. |
| 29 | 10A | B+power 12 V(special order vehicle). |
| 30 | 30A | Power driver seat (cutaway). Not used (spare) (stripped chassis). |
| 31 | – | Not used. |
| 32 | 20A | Vehicle power 1 – Powertrain control module. |
| 33 | 20A | Vehicle power 2 – Heater exhaust gas oxygen sensor 11. Heater exhaust gas oxygen sensor 12. Heater exhaust gas oxygen sensor 21. Canister vent solenoid. Canister purge solenoid. Variable camshaft timing. |
| 34 | 10A | Vehicle power 3 – Variable oil pressure control. Fan clutch. A/C clutch relay. |
| 35 | 20A | Vehicle power 4 – Coil on plug. |
| 36 | – | Not used. |
| 37 | – | Not used. |
| 38 | 10A | Washer relay (stripped chassis). Not used (spare) (cutaway). |
| 39 | – | Not used. |
| 41 | 30A | Trailer brake control connector. |
| 43 | 30A | Instrument panel connector (stripped chassis). Not used (spare) (cutaway). |
| 45 | – | Not used. |
| 46 | 10A | A/C clutch. |
| 47 | 40A | Upfitter relay 1 (cutaway). Not used (spare) (stripped chassis). |
| 48 | – | Not used. |
| 49 | 30A | Pump electronics module. |
| 50 | 15A | Fuel injectors. |
| 51 | 20A | Power point 1. |
| 52 | 50A | Power at all times Auxiliary A/C prep on B-pillar vehicle connector (cutaway). Not used (spare) (stripped chassis). |
| 53 | 30A | Trailer tow park lamps. |
| 54 | 40A | Run/start feed on instrument panel connector. |
| 55 | 20A | Upfitter 3 relay (cutaway). Not used (spare) (stripped chassis). |
| 56 | 20A | Power point 2 prep B-pillar connector. |
| 58 | 5A | USB smart charger. |
| 59 | 10A | Parking lampsl (special order vehicle). |
| 60 | – | Not used. |
| 61 | – | Not used. |
| 62 | – | Not used. |
| 63 | – | Not used. |
| 64 | – | Not used. |
| 65 | – | Not used. |
| 66 | – | Not used. |
| 67 | – | Not used. |
| 69 | – | Not used. |
| 70 | 40A | Inverter. |
| 71 | 30A | Anti-lock brake system valves. |
| 72 | 10A | Brake on and off switch. |
| 73 | – | Not used. |
| 74 | – | Not used. |
| 75 | – | Not used. |
| 76 | 60A | Anti-lock brake system pump. |
| 77 | 30A | Voltage quality module power – body control module. |
| 78 | 10A | Trailer tow stoplamps. |
| 79 | – | Not used. |
| 80 | 10A | Trailer tow backup lamps. |
| 81 | – | Not used. |
| 82 | 5A | Upfitter switch (factory location for ignition power). |
| 83 | 5A | Upfitter switch (optional location for power at all times). |
| 84 | – | Not used. |
| 85 | – | Not used. |
| 85 | – | Not used. |
| 87 | – | Not used. |
| 88 | – | Not used. |
| 89 | – | Not used. |
| 91 | 40A | Hot at all times / B+ power on B-pillar connector (cutaway). Battery power on instrument panel connector(stripped chassis). |
| 93 | 10A | Parking lamps 3 (special order vehicle). |
| 94 | 10A | Parking lamps 2 (special order vehicle). |
| 95 | 20A | Stoplamp relay. |
| 96 | – | Not used. |
| 97 | 50A | Battery power to engine, B-pillar and instrument panel vehicle connectors. |
| 98 | 30A | Trailer tow battery charge. |
| 99 | 40A | Upfitter 2 relay (cutaway). Not used (spare) (stripped chassis). |
| 100 | – | Not used. |
| 101 | – | Not used. |
| 102 | – | Not used. |
| 103 | – | Not used. |
| 104 | – | Not used. |
| 105 | 15A | Trailer tow right-hand and left-hand stoplamp and direction indicator relay power. |
| Note: Spare fuse amperage may vary. | ||
2025
Passenger Compartment Fuse Box
List of fuses in the passenger compartment fuse box (2025)
| № | A | Protected Component |
|---|---|---|
| 1 | – | Not used. |
| 2 | 10A | Left-hand front and right-hand front door lock switch (cutaway). Inverter (cutaway). Connector (stripped chassis). |
| 3 | 7.5A | Power mirror switch (cutaway). |
| – | Not used (stripped chassis). | |
| 4 | 20A | Not used (spare). |
| 5 | 20A | Not used (spare). |
| 6 | 10A | Not used (spare). |
| 7 | 10A | Not used (spare). |
| 8 | 5A | Not used (spare). |
| 9 | 5A | Not used (spare). |
| 10 | – | Not used. |
| 11 | – | Not used. |
| 12 | 7.5A | Smart datalink connector. |
| 13 | 7.5A | Cluster. Steering column control module. |
| 14 | 15A | Not used (spare). |
| 15 | 15A | Not used (spare). |
| 16 | – | Not used. |
| 17 | 7.5A | Not used. |
| 18 | 7.5A | Run/start feed for front blend actuator/climate mode switch (cutaway). Run/start feed to stripped chassis connector (stripped chassis). |
| 19 | 5A | Radio transceiver module and telematics control unit (cutaway). Telematics control unit (stripped chassis). |
| 20 | 5A | Ignition switch. |
| 21 | 5A | Not used. |
| 22 | 5A | Body builder B-pillar connector (cutaway). |
| 5A | Not used (stripped chassis). | |
| 23 | 30A | Not used (spare). |
| 24 | 30A | Not used (spare). |
| 25 | 20A | Not used (spare). |
| 26 | 30A | Not used (spare). |
| 27 | 30A | Not used (spare). |
| 28 | 30A | Not used (spare). |
| 29 | 15A | Upfitter interface module (cutaway). |
| – | Not used (stripped chassis). | |
| 30 | 5A | Not used (spare). |
| 31 | 10A | Smart datalink connector. |
| 32 | 20A | Radio (cutaway). |
| 33 | – | Not used. |
| 34 | 30A | Not used (spare). |
| 35 | 5A | Tow haul switch. |
| 36 | 15A | Rear view mirror (cutaway). Camera lane departure (cutaway). |
| – | Not used (stripped chassis). | |
| 37 | 20A | Not used (spare). |
| 38 | 30A | Power window switches and motors (cutaway). |
| – | Not used (stripped chassis). | |
| Note: Spare fuse amperage may vary. | ||
Engine Compartment Fuse Box
List of fuses in the engine compartment fuse box (2025)
| № | A | Protected Component |
|---|---|---|
| 1 | 20A | Horn. |
| 2 | 50A | Blower motor. |
| 3 | – | Not used. |
| 4 | 30A | Starter relay. |
| 5 | 20A | Power point 3. |
| 6 | 20A | Upfitter relay 4 (cutaway). Not used (spare) (stripped chassis). |
| 8 | – | Not used. |
| 10 | – | Not used. |
| 12 | 20A | Power point 4. |
| 13 | 10A | Yaw sensor (stripped chassis). Not used (spare) (cutaway). |
| 14 | 10A | Forward looking radar (cutaway). Not used (spare) (stripped chassis). |
| 15 | – | Not used. |
| 16 | – | Not used. |
| 17 | 10A | Powertrain control module run/start feed. |
| 18 | 10A | Anti-lock brake system run/start feed. |
| 19 | – | Not used. |
| 20 | 30A | Wiper power. |
| 21 | – | Not used. |
| 22 | 10A | Wiper module (stripped chassis). Not used (spare) (cutaway). |
| 23 | – | Not used. |
| 24 | 40A | Body control module – run power in feed 2. |
| 25 | 50A | Body control module – run power in feed 1. |
| 26 | – | Not used. |
| 27 | 20A | Body builder frame connector. |
| 28 | – | Not used. |
| 29 | 10A | B+ power 12 V (special order vehicle). |
| 30 | 30A | Power driver seat (cutaway). Not used (spare) (stripped chassis). |
| 31 | – | Not used. |
| 32 | 20A | Vehicle power 1 – Powertrain control module. |
| 33 | 20A | Vehicle power 2 – Heater exhaust gas oxygen sensor 11. Heater exhaust gas oxygen sensor 12. Heater exhaust gas oxygen sensor 21. Canister vent solenoid. Canister purge solenoid. Variable camshaft timing. |
| 34 | 10A | Vehicle power 3 – Variable oil pressure control. Fan clutch. A/C clutch relay. |
| 35 | 20A | Vehicle power 4 – Coil on plug. |
| 36 | – | Not used. |
| 37 | – | Not used. |
| 38 | 10A | Washer relay (stripped chassis). Not used (spare) (cutaway). |
| 39 | – | Not used. |
| 41 | 30A | Trailer brake control connector. |
| 43 | 30A | Instrument panel connector (stripped chassis). Notused (spare) (cutaway). |
| 45 | – | Not used. |
| 46 | 10A | A/C clutch. |
| 47 | 40A | Upfitter relay 1 (cutaway). Not used (spare) (stripped chassis). |
| 48 | – | Not used. |
| 49 | 30A | Pump electronics module. |
| 50 | 15A | Fuel injectors. |
| 51 | 20A | Power point 1. |
| 52 | 50A | Power at all times Auxiliary A/C prep on B-pillar vehicle connector (cutaway). Not used (spare) (stripped chassis). |
| 53 | 30A | Trailer tow park lamps. |
| 54 | 40A | Run/start feed on instrument panel connector. |
| 55 | 20A | Upfitter 3 relay (cutaway). Not used (spare) (stripped chassis). |
| 56 | 20A | Power point 2 prep B-pillar connector. |
| 58 | 5A | USB smart charger. |
| 59 | 10A | Parking lampsl (special order vehicle). |
| 60 | – | Not used. |
| 61 | – | Not used. |
| 62 | – | Not used. |
| 63 | – | Not used. |
| 64 | – | Not used. |
| 65 | – | Not used. |
| 66 | – | Not used. |
| 67 | – | Not used. |
| 69 | – | Not used. |
| 70 | 40A | Inverter. |
| 71 | 30A | Anti-lock brake system valves. |
| 72 | 10A | Brake on and off switch. |
| 73 | – | Not used. |
| 74 | – | Not used. |
| 75 | – | Not used. |
| 76 | 60A | Anti-lock brake system pump. |
| 77 | 30A | Voltage quality module power – body control module. |
| 78 | 10A | Trailer tow stoplamps. |
| 79 | – | Not used. |
| 80 | 10A | Trailer tow backup lamps. |
| 81 | – | Not used. |
| 82 | 5A | Upfitter switch (factory location for ignition power). |
| 83 | 5A | Upfitter switch (optional location for power at all times). |
| 84 | – | Not used. |
| 85 | – | Not used. |
| 85 | – | Not used. |
| 87 | – | Not used. |
| 88 | – | Not used. |
| 89 | – | Not used. |
| 91 | 40A | Hot at all times / B+power on B-pillar connector (cutaway). Battery power on instrument panel connector (stripped chassis). |
| 93 | 10A | Parking lamps 3 (special order vehicle). |
| 94 | 10A | Parking lamps 2 (special order vehicle). |
| 95 | 20A | Stoplamp relay. |
| 96 | – | Not used. |
| 97 | 50A | Battery power to engine, B-pillarand instrument panel vehicle connectors. |
| 98 | 30A | Trailer tow battery charge. |
| 99 | 40A | Upfitter 2 relay (cutaway). Not used (spare) (stripped chassis). |
| 100 | – | Not used. |
| 101 | – | Not used. |
| 102 | – | Not used. |
| 103 | – | Not used. |
| 104 | – | Not used. |
| 105 | 15A | Trailer tow right-hand and left-hand stoplamp and direction indicator relay power. |
| Note: Spare fuse amperage may vary. | ||
Conclusion
The Ford E-350 and E-450 (2021-2025) offer unmatched utility and durability for commercial use. Maintaining the fuse box and relays is essential for consistent performance.
